Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RARB | P10826 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073768 | 0.91 | HTT (0.68) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL11921516 | 0.90 | THRB (0.55) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL22566492 | 0.88 | THRB (0.53) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL22781567 | 0.88 | HTT (0.72) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL27906313 | 0.86 | ELANE (0.57) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL1152389 | 0.85 | TDP1 (0.64) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL27973892 | 0.85 | HCAR2 (0.49) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL42893 | 0.85 | HCAR2 (0.51) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL10457799 | 0.85 | THRB (0.50) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL13932757 | 0.84 | CYP4A11 (0.54) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781496-B2 | High refractive-index, hydrophilic monomers and polymers, and ophthalmic devices comprising such polymers | BAUSCH & LOMB INCORPORATED (US) | 2010-08-24 | — | — | US | disclosed |
| US-7781496-B2 | High refractive-index, hydrophilic monomers and polymers, and ophthalmic devices comprising such polymers | BAUSCH & LOMB INCORPORATED (US) | 2010-08-24 | — | — | US | disclosed |
| US-RE41579-E1 | Positive type photosensitive image-forming material for use with an infrared laser | FUJIFILM CORPORATION (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20090076187-A1 | High Refractive-Index, Hydrophilic Monomers and Polymers, and Ophthalmic Devices Comprising Such Polymers | SALIX PHARMACEUTICALS, LTD. | 2009-03-19 | — | — | US | disclosed |
| US-20090076187-A1 | High Refractive-Index, Hydrophilic Monomers and Polymers, and Ophthalmic Devices Comprising Such Polymers | SALIX PHARMACEUTICALS, LTD. | 2009-03-19 | — | — | US | disclosed |
| US-7495061-B2 | High refractive-index, hydrophilic monomers and polymers, and ophthalmic devices comprising such polymers | BAUSCH + LOMB INCORPORATED (US) | 2009-02-24 | — | — | US | disclosed |
| US-7495061-B2 | High refractive-index, hydrophilic monomers and polymers, and ophthalmic devices comprising such polymers | BAUSCH + LOMB INCORPORATED (US) | 2009-02-24 | — | — | US | disclosed |
| US-20080183006-A1 | High Refractive-Index, Hydrophilic Monomers and Polymers, and Ophthalmic Devices Comprising Such Polymers | SALAMONE JOSEPH C | 2008-07-31 | — | — | US | disclosed |
| US-20080183006-A1 | High Refractive-Index, Hydrophilic Monomers and Polymers, and Ophthalmic Devices Comprising Such Polymers | SALAMONE JOSEPH C | 2008-07-31 | — | — | US | disclosed |
| EP-1219464-B1 | Lithographic printing plate precursor | FUJIFILM CORP (JP) | 2008-02-13 | — | — | EP | disclosed |
| EP-0909657-B1 | A positive type photosensitive image-forming material for an infrared laser | FUJI PHOTO FILM CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-6573022-B1 | Planographic printing plate; roughened aluminum layered with alkali soluble resins, light absorbing heat generating com-pound and a sulfone; developmental latitude | FUJI PHOTO FILM CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| US-20020182538-A1 | Capable of plate-making by scanning exposure based on digital signals, high sensitivity, free of residual color and residual film phenomena, and excellent in resistance to smearing (i.e., staining) and excellent in press life | FUJIFILM CORPORATION (JP) | 2002-12-05 | — | — | US | disclosed |
| EP-1258369-A2 | A positive type photosensitive image-forming material for an infrared laser and a positive type photosensitive composition for an infrared laser | FUJI PHOTO FILM CO., LTD. (JP) | 2002-11-20 | — | — | EP | disclosed |
| EP-1219464-A2 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-20020081522-A1 | Positive type photosensitive image-forming material for an infrared laser and a positive type photosensitive composition for an infrared laser | FUJIFILM CORPORATION (JP) | 2002-06-27 | — | — | US | disclosed |
| US-6340551-B1 | ARE CAPABLE OF DIRECTLY MAKING A PRINTING PLATE USING AN INFRARED LASER BASED ON DIGITAL SIGNALS OUTPUTTED FROM A COMPUTER | FUJI FILM CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| US-6238839-B1 | DIMENSIONALLY STABLE METAL SUPPORT COATED WITH A HEAT-INSULATING LAYER, A HYDROPHILIC LAYER AND A THERMOSENSITIVE LIPOPHILIC LAYER; IMAGE QUALITY, MULTICOLOR PRINTS | FUJI PHOTO FILM CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-1078736-A1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |
| EP-0909657-A2 | A positive type photosensitive image-forming material for an infrared laser and a positive type photosensitive composition for an infrared laser | FUJI PHOTO FILM CO., LTD (JP) | 1999-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080183006-A1 | High Refractive-Index, Hydrophilic Monomers and Polymers, and Ophthalmic Devices Comprising Such Polymers | UACA, PITHD1, ARID2 | POLB 4291/4885APEX1 856/4885HTT 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.