Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 15/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25373928 | 0.82 | P2RX4 (0.55) | ANO1P2RX4ROCK2 | |
| SCHEMBL30403121 | 0.79 | ALDH1A1 (0.50) | ANO1ROCK2 | |
| SCHEMBL30368260 | 0.75 | ANO1 (0.53) | ANO1ROCK2RECQL | |
| SCHEMBL30402844 | 0.73 | ANO1 (0.61) | ANO1ROCK2RECQL | |
| SCHEMBL30402922 | 0.72 | ANO1 (0.61) | ANO1P2RX4 | |
| SCHEMBL2184568 | 0.72 | WNT3A (0.59) | ANO1 | |
| SCHEMBL26186570 | 0.71 | P2RX4 (0.58) | ANO1P2RX4ROCK2RECQL | |
| SCHEMBL25373470 | 0.71 | P2RX4 (0.60) | ANO1P2RX4ROCK2RECQL | |
| SCHEMBL19576777 | 0.71 | P2RX4 (0.61) | P2RX4ROCK2 | |
| SCHEMBL29029217 | 0.71 | ROCK2 (0.48) | ANO1P2RX4ROCK2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989218-A | Use of N-phenylacetamides having P2X4 receptor antagonistic activity for the treatment of certain eye diseases | 拜耳公司 | 2023-04-18 | — | — | CN | disclosed |