SCHEMBL30403239

SCHEMBL30403239

Cc1c(Br)cccc1C(=O)c1ccccc1F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.47
CES1 P23141 2/20 0.47
GAA P10253 1/20 0.44
ALDH1A1 P00352 3/20 0.44
ALOX15 P16050 1/20 0.44
PRNP P04156 1/20 0.42
MAOB P27338 1/20 0.42
MAPT P10636 2/20 0.41
HTT P42858 1/20 0.40
BCHE P06276 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
RAB9A P51151 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
TAS1R2 Q8TE23 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11089840 0.87 PRNP (0.47) GAAALDH1A1PRNPMAOBMAPT
SCHEMBL31470059 0.83 CES2 (0.56) CES2CES1GAAALDH1A1ALOX15
SCHEMBL30402632 0.79 AGER (0.52) CES2CES1GAAALDH1A1ALOX15
SCHEMBL30293901 0.79 CES2 (0.71) CES2CES1GAAALDH1A1ALOX15
SCHEMBL250099 0.79 CES2 (0.71) CES2CES1GAAALDH1A1ALOX15
SCHEMBL11843627 0.79 AKR1C3 (0.52) GAAALDH1A1PRNPMAPTSMN1; SMN2
SCHEMBL31574193 0.77 CES2 (0.68) CES2CES1GAAALDH1A1ALOX15
Hydrochloric Acid SCHEMBL27733532 0.77 CES2 (0.68) CES2CES1GAAALDH1A1ALOX15
SCHEMBL27185988 0.77 CES2 (0.68) CES2CES1GAAALDH1A1ALOX15
SCHEMBL149172 0.76 AGER (0.53) GAAALDH1A1MAPTHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082203-A Shulin acid intermediate impurity and preparation method thereof 宁波大红鹰药业股份有限公司 2023-05-09 CN disclosed