Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30403239 | 0.87 | CES2 (0.47) | PRNPALDH1A1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL11843627 | 0.86 | AKR1C3 (0.52) | PRNPALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL29621571 | 0.84 | TSHR (0.52) | PRNPALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL4443208 | 0.84 | ALDH1A1 (0.40) | PRNPALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL211283 | 0.84 | TSHR (0.52) | PRNPALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL6469935 | 0.84 | ALDH1A1 (0.40) | PRNPALDH1A1HPGDHSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL15351222 | 0.83 | TSHR (0.50) | PRNPALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL16357915 | 0.83 | ALDH1A1 (0.39) | PRNPALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL3710686 | 0.83 | ALDH1A1 (0.42) | PRNPALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL1363612 | 0.83 | METAP2 (0.45) | ALDH1A1HPGDHSD17B10GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4467102-A | RACEMIC MODIFICATION WITH BRUCINE | UBE INDUSTRIES, LTD. (JP) | 1984-08-21 | — | — | US | disclosed |