Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302085 | 0.83 | CNR2 (0.47) | NPC1CNR2LMNAPOLBHTT | |
| SCHEMBL304739 | 0.78 | CNR2 (0.43) | NPC1RAB9ACNR2KMT2ALMNA | |
| SCHEMBL3275899 | 0.76 | HTR2C (0.49) | NPC1RAB9ACNR2LMNAALDH1A1 | |
| SCHEMBL2188016 | 0.74 | KDM4E (0.43) | NPC1KMT2ALMNAPOLBALDH1A1 | |
| SCHEMBL3275051 | 0.74 | HTR2C (0.45) | NPC1RAB9ACNR2KMT2AALDH1A1 | |
| SCHEMBL301863 | 0.73 | MEN1 (0.49) | NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL302155 | 0.73 | MEN1 (0.47) | NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL1971605 | 0.72 | CNR2 (0.38) | NPC1RAB9ACNR2KMT2ALMNA | |
| SCHEMBL3260086 | 0.72 | TSHR (0.39) | NPC1RAB9ACNR2KMT2ALMNA | |
| SCHEMBL1976194 | 0.71 | CNR2 (0.39) | NPC1RAB9ACNR2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500835-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2334637-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-06-22 | — | — | EP | claimed |
| EP-2334637-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-06-22 | — | — | EP | disclosed |