SCHEMBL30404053

SCHEMBL30404053

Oc1cc(F)c(Cl)cc1Cc1cc(Cl)c(F)cc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 3/20 0.46
HPGD P15428 3/20 0.46
MAPT P10636 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
CYP3A4 P08684 3/20 0.46
ALOX15 P16050 2/20 0.46
HSP90AA1 P07900 2/20 0.46
SLC22A1 O15245 1/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
HSPD1 P10809 1/20 0.46
HSPA5 P11021 1/20 0.46
IDO1 P14902 1/20 0.46
ALOX12 P18054 1/20 0.46
CASP1 P29466 1/20 0.46
HTT P42858 1/20 0.46
BLM P54132 1/20 0.46
HSPE1 P61604 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69620 0.82 CYP3A4 (0.58) HIF1AHPGDMAPTMEN1KMT2A
SCHEMBL1905388 0.79 ERCC1 (0.35) HPGDMEN1KMT2ACYP3A4HTT
SCHEMBL29940963 0.77 CA3 (0.40) HPGDMAPTMEN1KMT2ACYP3A4
SCHEMBL11714444 0.77 HSD17B10 (0.60) HPGDMAPTCYP3A4HSP90AA1CASP1
SCHEMBL5504180 0.74 MEN1 (0.45) HIF1AHPGDMAPTMEN1KMT2A
SCHEMBL6535477 0.74 LMNA (0.50) HIF1AHPGDMAPTMEN1KMT2A
SCHEMBL14396118 0.73 HSD17B10 (0.36) HPGDMAPTMEN1KMT2ACYP3A4
SCHEMBL5881462 0.73 HSD17B10 (0.42) HPGDMAPTMEN1KMT2ACYP3A4
SCHEMBL911775 0.72 TSHR (0.60) HPGDMAPTMEN1KMT2ACYP3A4
SCHEMBL31357885 0.72 TSHR (0.60) HPGDMAPTMEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116102474-B Di-connected dihalogen phenol and derivative thereof, preparation method and application 上海霖陵化工科技有限公司 2025-04-25 CN claimed
CN-116102474-B Di-connected dihalogen phenol and derivative thereof, preparation method and application 上海霖陵化工科技有限公司 2025-04-25 CN disclosed
CN-116102474-A Di-connected dihalogen phenol and derivative thereof, preparation method and application 上海霖陵化工科技有限公司 2023-05-12 CN disclosed