Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 14/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 14/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.43 |
| ▸ | NRP1 | O14786 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20694557 | 0.93 | OPRM1 (0.43) | OPRM1OPRK1EPHA2NRP1 | |
| SCHEMBL22803172 | 0.91 | OPRM1 (0.43) | OPRM1OPRK1EPHA2NRP1 | |
| SCHEMBL29572497 | 0.90 | OPRM1 (0.55) | OPRM1OPRK1APLNR | |
| SCHEMBL29571998 | 0.90 | OPRM1 (0.48) | OPRM1OPRK1EPHA2NRP1APLNR | |
| SCHEMBL30416412 | 0.86 | GRB2 (0.47) | OPRM1OPRK1EPHA2NRP1 | |
| SCHEMBL29802094 | 0.86 | OPRM1 (0.45) | OPRM1OPRK1EPHA2NRP1 | |
| SCHEMBL22872708 | 0.85 | NRP1 (0.54) | OPRM1OPRK1EPHA2NRP1 | |
| SCHEMBL20694547 | 0.85 | NRP1 (0.46) | OPRM1OPRK1EPHA2NRP1 | |
| SCHEMBL35402417 | 0.85 | OPRM1 (0.44) | OPRM1OPRK1EPHA2 | |
| SCHEMBL29535207 | 0.84 | OPRM1 (0.52) | OPRM1OPRK1EPHA2NRP1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685766-B2 | 14-3-3 targeting peptides for cancer treatment | CREIGHTON UNIVERSITY (US) | 2023-06-27 | — | — | US | disclosed |