⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876478 | 0.78 | — | — | |
| SCHEMBL15871027 | 0.69 | RAB9A (0.63) | — | |
| SCHEMBL16597642 | 0.69 | RAB9A (0.63) | — | |
| SCHEMBL1253601 | 0.69 | CTH (0.47) | — | |
| SCHEMBL17185663 | 0.67 | — | — | |
| SCHEMBL5623070 | 0.66 | — | — | |
| SCHEMBL291278 | 0.66 | — | — | |
| SCHEMBL195894 | 0.66 | — | — | |
| SCHEMBL445202 | 0.66 | — | — | |
| SCHEMBL193827 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444300-A2 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |