Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | ATXN2 | Q99700 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31578988 | 0.84 | KIT (0.42) | GPR119 | |
| SCHEMBL25240539 | 0.83 | PDGFRB (0.39) | PDGFRBALDH1A1HPGDKRASACHE | |
| SCHEMBL30405747 | 0.82 | HTT (0.48) | HTTPDGFRBENPP2ATXN2MAPT | |
| SCHEMBL30406045 | 0.81 | MAPK7 (0.44) | ENPP2ATXN2MTNR1B | |
| SCHEMBL30405246 | 0.79 | OPRD1 (0.38) | HTTGPR119ENPP2ATXN2MAPT | |
| SCHEMBL30405798 | 0.78 | OPRD1 (0.43) | PDGFRBENPP2ATXN2MTNR1BOPRD1 | |
| SCHEMBL30405888 | 0.78 | PDGFRB (0.41) | PDGFRBENPP2ATXN2SMN1; SMN2MTNR1B | |
| SCHEMBL30405875 | 0.77 | PDGFRB (0.39) | HTTPDGFRBENPP2ATXN2MAPT | |
| SCHEMBL30406184 | 0.77 | OPRD1 (0.38) | HTTGPR119ENPP2ATXN2MAPT | |
| SCHEMBL31578997 | 0.77 | KIT (0.42) | GPR119PDGFRBACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444300-A2 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |