Ophioglonol

Ophioglonol

SCHEMBL30406715

O=c1c(CO)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLH Q9Y253 10/20 0.76
KDM4E B2RXH2 7/20 0.71
MEN1 O00255 6/20 0.71
KMT2A Q03164 6/20 0.71
GAA P10253 6/20 0.71
HSD17B10 Q99714 5/20 0.71
POLB P06746 5/20 0.71
MAPT P10636 5/20 0.71
AKR1B1 P15121 5/20 0.71
RECQL P46063 4/20 0.71
TP53 P04637 4/20 0.71
CYP1A2 P05177 4/20 0.71
CYP3A4 P08684 4/20 0.71
CYP2C9 P11712 4/20 0.71
ALOX15 P16050 4/20 0.71
HIF1A Q16665 4/20 0.71
CA12 O43570 4/20 0.71
SLCO2B1 O94956 4/20 0.71
CA2 P00918 4/20 0.71
CA7 P43166 4/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5169608 0.90 POLH (0.80) POLHKDM4EMEN1KMT2AGAA
SCHEMBL31485716 0.90 POLH (0.80) POLHKDM4EMEN1KMT2AGAA
SCHEMBL7202185 0.88 POLH (0.82) POLHKDM4EMEN1KMT2AGAA
SCHEMBL25308157 0.86 POLH (1.00) POLHKDM4EMEN1KMT2AGAA
SCHEMBL3032358 0.86 POLH (0.71) POLHKDM4EMEN1KMT2AGAA
SCHEMBL30663833 0.86 POLH (1.00) POLHKDM4EMEN1KMT2AGAA
SCHEMBL3718557 0.85 POLH (0.69) POLHKDM4EMEN1KMT2AGAA
Quercetin SCHEMBL17629824 0.83 MEN1 (1.00) POLHKDM4EMEN1KMT2AGAA
Quercetin SCHEMBL19723 0.83 MEN1 (1.00) POLHKDM4EMEN1KMT2AGAA
Quercetin SCHEMBL118425 0.83 MEN1 (1.00) POLHKDM4EMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116327736-A Composite nano-particle with pancrelipase inhibition effect and preparation method thereof 江南大学 2023-06-27 CN disclosed