Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 10/20 | 0.69 |
| ▸ | MEN1 | O00255 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.65 |
| ▸ | RECQL | P46063 | 5/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.65 |
| ▸ | IPMK | Q8NFU5 | 5/20 | 0.65 |
| ▸ | IP6K2 | Q9UHH9 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | TP53 | P04637 | 4/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | APP | P05067 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ophioglonol SCHEMBL30406715 | 0.85 | POLH (0.76) | POLHMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL7202185 | 0.84 | POLH (0.82) | POLHMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL31485716 | 0.83 | POLH (0.80) | POLHMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL5169608 | 0.83 | POLH (0.80) | POLHMEN1KMT2AKDM4EHSD17B10 | |
| Quercetin SCHEMBL1148195 | 0.83 | MEN1 (0.90) | POLHMEN1KMT2AKDM4EHSD17B10 | |
| Quercetin SCHEMBL30512465 | 0.83 | MEN1 (0.90) | POLHMEN1KMT2AKDM4EHSD17B10 | |
| Quercetin SCHEMBL4473368 | 0.83 | MEN1 (0.90) | POLHMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL25308157 | 0.82 | POLH (1.00) | POLHMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL3032358 | 0.82 | POLH (0.71) | POLHMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL30663833 | 0.82 | POLH (1.00) | POLHMEN1KMT2AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297020-A1 | PHOSPHORYLATED AND PHOSPHONATED PYRONE ANALOGS FOR THERAPEUTIC TREATMENT | LIMERICK BIOPHARMA, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| WO-2010129138-A2 | PHOSPHORYLATED AND PHOSPHONATED PYRONE ANALOGS FOR THERAPEUTIC TREATMENT | LIMERICK BIOPHARMA (US) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297020-A1 | PHOSPHORYLATED AND PHOSPHONATED PYRONE ANALOGS FOR THERAPEUTIC TREATMENT | PC, PCK1, PYGL | POLH 2494/4885MEN1 2302/4885KMT2A 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.