SCHEMBL3040797

SCHEMBL3040797

CC(C)(NS(=O)(=O)c1ccc(Br)cc1C(F)(F)F)C1CC1

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 18/20 0.63
CNR1 P21554 6/20 0.63
PFKFB3 Q16875 1/20 0.41
PPARG P37231 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14995856 0.83 PFKFB3 (0.46) CNR2CNR1PFKFB3PPARG
SCHEMBL2372639 0.79 CNR2 (0.48) CNR2CNR1PFKFB3
SCHEMBL2371777 0.78 PFKFB3 (0.46) CNR2CNR1PFKFB3PPARG
SCHEMBL3036367 0.78 CNR2 (1.00) CNR2CNR1
SCHEMBL3036786 0.77 CNR2 (1.00) CNR2CNR1
SCHEMBL3042516 0.77 CNR2 (1.00) CNR2CNR1
SCHEMBL3018967 0.77 HTT (0.49) CNR2CNR1PFKFB3
SCHEMBL3018096 0.76 CNR2 (0.67) CNR2CNR1
SCHEMBL3038867 0.75 CNR2 (1.00) CNR2CNR1
SCHEMBL2371775 0.75 PFKFB3 (0.46) CNR2CNR1PFKFB3PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9422235-B2 Sulfonamide derivatives with therapeutic indications PHARMOS CORPORATION (US) 2016-08-23 US disclosed
US-20100056528-A1 SULFONAMIDE DERIVATIVES WITH THERAPEUTIC INDICATIONS PHARMOS CORPORATION 2010-03-04 US disclosed
EP-2139852-A1 SULFONAMIDE DERIVATIVES WITH THERAPEUTIC INDICATIONS Pharmos Corporation (US) 2010-01-06 EP disclosed
WO-2008075353-A1 SULFONAMIDE DERIVATIVES WITH THERAPEUTIC INDICATIONS PHARMOS CORPORATION (US) 2008-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056528-A1 SULFONAMIDE DERIVATIVES WITH THERAPEUTIC INDICATIONS SULT2A1, STS, SULT1A1 CNR2 41/4885CNR1 207/4885PFKFB3 2124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.