Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008005 | 0.74 | ALDH1A1 (0.63) | ALDH1A1HTTKMT2AKDM4ETDP1 | |
| SCHEMBL27792482 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HTTKMT2AKDM4ETDP1 | |
| SCHEMBL9178803 | 0.71 | ALDH1A1 (0.56) | ALDH1A1HTTKMT2AKDM4ETDP1 | |
| SCHEMBL5886755 | 0.71 | ALDH1A1 (0.52) | ALDH1A1HTTKMT2AKDM4ETDP1 | |
| SCHEMBL30409307 | 0.71 | NPSR1 (0.50) | ALDH1A1HTTKMT2AKDM4ENPSR1 | |
| SCHEMBL30410326 | 0.70 | NPSR1 (0.62) | ALDH1A1HTTKMT2ATDP1NPSR1 | |
| SCHEMBL28791340 | 0.70 | DGAT1 (0.35) | — | |
| SCHEMBL30408992 | 0.69 | NPSR1 (0.55) | ALDH1A1HTTKMT2AKDM4ETDP1 | |
| SCHEMBL19716283 | 0.69 | RAB9A (0.70) | ALDH1A1HTTKMT2AKDM4ETDP1 | |
| SCHEMBL27453993 | 0.69 | MAPT (0.43) | ALDH1A1KMT2AKDM4EL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016611-B1 | TRIPEPTIDES, PROCESS FOR THEIR PREPARATION, THERAPEUTIC COMPOSITIONS CONTAINING THEM AND METHODS FOR THEIR USE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-08-17 | — | — | EP | disclosed |
| US-4258151-A | IMMUNOLOGY AND THYMOLYTIC USES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1981-03-24 | — | — | US | disclosed |
| US-4232008-A | THYMIC FUNCTION AND IMMUNITY | ORTHO PHARMACEUTICAL CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4215112-A | IMMUNOLOGY; GLANDULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1980-07-29 | — | — | US | disclosed |
| US-4190647-A | INDUCE DIFFERENTIATION OF T-LYMPHOCYTES AND COMPLEMENT RECEPTOR (CR+) B-LYMPHOCYTES, USEFUL AS THYMIC FUNCTION AND IMMUNITY DRUGS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1980-02-26 | — | — | US | disclosed |
| US-4055568-A | YELLOW | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |
| US-4002740-A | POLYPEPTIDES USED IN TREATING FUNGAL INFECTIONS, MYCOPLASMA INFECTIONS, TUBERCULOSIS, LEPROSY, AND VIRAL INFECTIONS | GOLDSTEIN GIDEON | 1977-01-11 | — | — | US | disclosed |