Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1855234 | 1.00 | PTGS2 (0.33) | PTGS2L3MBTL1IKBKBMEN1NPC1 | |
| SCHEMBL1711432 | 0.82 | ALDH1A1 (0.39) | L3MBTL1MEN1KMT2AEPRS1 | |
| SCHEMBL31586624 | 0.82 | ALDH1A1 (0.39) | L3MBTL1MEN1KMT2AEPRS1 | |
| SCHEMBL30139591 | 0.80 | DGAT1 (0.40) | IKBKBMEN1KMT2A | |
| SCHEMBL20917216 | 0.80 | DGAT1 (0.40) | IKBKBMEN1KMT2A | |
| SCHEMBL12022696 | 0.80 | IKBKB (0.34) | PTGS2L3MBTL1IKBKBMEN1NPC1 | |
| SCHEMBL10321009 | 0.80 | — | — | |
| SCHEMBL31316470 | 0.79 | NPSR1 (0.47) | L3MBTL1NPC1GAARAB9A | |
| SCHEMBL21383676 | 0.79 | NPSR1 (0.47) | L3MBTL1NPC1GAARAB9A | |
| SCHEMBL27775511 | 0.79 | TSHR (0.35) | L3MBTL1NPC1GAARAB9ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739669-A1 | SODIUM CHANNEL BLOCKERS | Novartis AG (CH) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025125665-A1 | FURTHER SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025011450-A1 | SODIUM CHANNEL BLOCKERS | NOVARTIS AG (CH) | 2025-01-16 | — | — | WO | disclosed |
| WO-2023078337-A1 | CDK8/19 DUAL INHIBITORS AND METHODS OF USE | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-11 | — | — | WO | disclosed |