Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.37 |
| ▸ | GPR183 | P32249 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30410284 | 0.90 | MGLL (0.39) | MGLLCYP11B1CYP11B2 | |
| SCHEMBL25146135 | 0.90 | MGLL (0.46) | MGLLGPR183P2RX7SLC6A2SLC6A4 | |
| SCHEMBL30409565 | 0.88 | MGLL (0.43) | MGLL | |
| SCHEMBL30410167 | 0.86 | MGLL (0.41) | MGLLSLC6A4CYP11B1CYP11B2 | |
| SCHEMBL30408797 | 0.84 | MGLL (0.36) | MGLLCYP11B1CYP11B2 | |
| SCHEMBL30410100 | 0.83 | MGLL (0.37) | MGLLGPR183P2RX7SLC6A2SLC6A4 | |
| SCHEMBL30409386 | 0.81 | ENPP2 (0.37) | MGLL | |
| SCHEMBL30409661 | 0.81 | CACNA1B (0.35) | MGLLCYP11B1CYP11B2 | |
| SCHEMBL31549767 | 0.79 | P2RX7 (0.38) | MGLLGPR183P2RX7SLC6A2SLC6A4 | |
| SCHEMBL25146310 | 0.79 | MGLL (0.49) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4416154-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-08-21 | — | — | EP | claimed |
| CN-118103374-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2024-05-28 | — | — | CN | claimed |
| WO-2023062049-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | claimed |
| EP-4416154-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-08-21 | — | — | EP | disclosed |
| CN-118103374-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2023062049-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | disclosed |