Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1837614 | 1.00 | TRPM8 (0.33) | TRPM8NPSR1PTGS1PTGS2CYP19A1 | |
| SCHEMBL15520394 | 0.98 | PTGS1 (0.33) | TRPM8NPSR1PTGS1PTGS2CYP19A1 | |
| SCHEMBL30409561 | 0.86 | GABRA1 (0.34) | NPSR1PTGS1CYP19A1LMNAMEN1 | |
| SCHEMBL1837910 | 0.86 | GABRA1 (0.34) | NPSR1PTGS1CYP19A1LMNAMEN1 | |
| SCHEMBL15519291 | 0.84 | GABRA1 (0.35) | NPSR1PTGS1PTGS2CYP19A1LMNA | |
| SCHEMBL1837157 | 0.78 | GABRA1 (0.46) | NPSR1CYP19A1LMNAMEN1KMT2A | |
| SCHEMBL1846694 | 0.76 | GABRA1 (0.47) | LMNAMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL1841094 | 0.72 | ADRB2 (0.34) | TRPM8LMNAMEN1KMT2AADRB2 | |
| SCHEMBL1834148 | 0.70 | ADRB2 (0.31) | TRPM8ADRB2ADRB1 | |
| SCHEMBL1834041 | 0.70 | ADRB2 (0.35) | TRPM8ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023080257-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION | 旭化成株式会社 | 2023-05-11 | — | — | WO | disclosed |