Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | BPTF | Q12830 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2266479 | 1.00 | HTR2A (0.54) | HTR2AHTR2CHTR6MAPTHTT | |
| SCHEMBL2264937 | 0.92 | BPTF (0.47) | HTR2AHTR2CMAPTHTTRXFP1 | |
| SCHEMBL1122371 | 0.89 | HTR7 (0.58) | HTR2AHTR2CHTR6MAPTHTT | |
| SCHEMBL30410682 | 0.86 | HTR6 (0.51) | HTR6MAPTRXFP1HTR7PLG | |
| SCHEMBL4007951 | 0.86 | HTR6 (0.51) | HTR6MAPTRXFP1HTR7PLG | |
| SCHEMBL3355607 | 0.84 | HTR7 (0.49) | MAPTHTR7PLGPLAUSLC6A2 | |
| SCHEMBL3139096 | 0.82 | HTR6 (0.71) | HTR6EGFR | |
| SCHEMBL2479169 | 0.82 | HTR7 (0.47) | MAPTHTR7PLGPLAUSLC6A2 | |
| SCHEMBL16371052 | 0.81 | PLG (0.46) | MAPTHTR7PLGPLAUSLC6A2 | |
| SCHEMBL30672928 | 0.81 | PLG (0.46) | MAPTHTR7PLGPLAUSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245484-A1 | FOXN1 ACTIVATORS | THYMOFOX INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| CN-116143773-B | 2-amino-4-thiazolylpyrimidine compound and preparation method and application thereof | 中国药科大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-116143773-A | 2-amino-4-thiazolylpyrimidine compound and preparation method and application thereof | 中国药科大学 | 2023-05-23 | — | — | CN | disclosed |