Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3041196 | 0.78 | TDP1 (0.35) | NCEH1GAAKDM4EHPGDL3MBTL1 | |
| SCHEMBL29620186 | 0.72 | MAPT (0.58) | KMT2APOLBSMN1; SMN2MEN1HTT | |
| SCHEMBL702988 | 0.72 | MAPT (0.58) | KMT2APOLBSMN1; SMN2MEN1HTT | |
| SCHEMBL10345808 | 0.69 | ALOX5 (0.51) | KMT2APOLBALDH1A1GAASMN1; SMN2 | |
| SCHEMBL15414250 | 0.69 | ALOX5 (0.51) | NCEH1KMT2AALDH1A1NPSR1HSD17B10 | |
| SCHEMBL15564688 | 0.68 | PRMT5 (0.41) | NCEH1KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL15414084 | 0.68 | MAPT (0.54) | NCEH1KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL3041847 | 0.67 | ALDH1A1 (0.49) | NCEH1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10456727 | 0.67 | PRMT5 (0.46) | KMT2AALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL313000 | 0.66 | MAPT (0.49) | NCEH1KMT2APOLBSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647878-B2 | Highly refractive immersion liquids and their use | CARL ZEISS AG (DE) | 2014-02-11 | — | — | US | disclosed |
| US-20100212547-A1 | Highly Refractive Immersion Liquids And Their Use | CARL ZEISS AG (DE) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100212547-A1 | Highly Refractive Immersion Liquids And Their Use | NR4A3, NR2E3, NR4A1 | NCEH1 1797/4885KMT2A 3367/4885POLB 3554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.