Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17491542 | 0.72 | AR (0.40) | AREGFRALDH1A1GAAMAPT | |
| SCHEMBL30413143 | 0.72 | EGFR (0.37) | AREGFR | |
| SCHEMBL24568075 | 0.67 | RET (0.33) | GRM5 | |
| SCHEMBL13035938 | 0.66 | ALDH1A1 (0.35) | AREGFRALDH1A1GAAMAPT | |
| SCHEMBL29620781 | 0.66 | ALDH1A1 (0.35) | AREGFRALDH1A1GAAMAPT | |
| SCHEMBL24254608 | 0.66 | ADRA2A (0.37) | AREGFRALDH1A1GAAMAPT | |
| SCHEMBL17077824 | 0.66 | RET (0.32) | DHFR | |
| SCHEMBL382392 | 0.64 | GRM5 (0.51) | AREGFRALDH1A1GAAMAPT | |
| SCHEMBL1812071 | 0.64 | ALDH1A1 (0.33) | DHFRALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL17799382 | 0.62 | AR (0.53) | AREGFRALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182322-A1 | PYRIDO OXAZINE DERIVATIVES AS ALK5 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2023-05-24 | — | — | EP | disclosed |