Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 13/20 | 0.57 |
| ▸ | BCR | P11274 | 11/20 | 0.57 |
| ▸ | SRC | P12931 | 9/20 | 0.57 |
| ▸ | PLK1 | P53350 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | PRKACA | P17612 | 1/20 | 0.57 |
| ▸ | PRKACG | P22612 | 1/20 | 0.57 |
| ▸ | PRKACB | P22694 | 1/20 | 0.57 |
| ▸ | ABL2 | P42684 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.54 |
| ▸ | PRKCA | P17252 | 4/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823928 | 0.93 | ABL1 (0.58) | ABL1BCRSRCPLK1ABL2 | |
| SCHEMBL3041252 | 0.89 | MAPK8 (0.57) | ABL1BCRSRCPLK1ABL2 | |
| SCHEMBL823915 | 0.80 | CAMK2D (0.82) | CAMK2DABL1BCRSRCPLK1 | |
| SCHEMBL25337094 | 0.78 | ABL1 (0.75) | CAMK2DABL1BCRSRCPLK1 | |
| SCHEMBL31118910 | 0.78 | ABL1 (0.75) | CAMK2DABL1BCRSRCPLK1 | |
| SCHEMBL2945644 | 0.77 | PLK1 (0.79) | CAMK2DABL1BCRSRCPLK1 | |
| SCHEMBL12801111 | 0.77 | PLK1 (0.64) | CAMK2DABL1BCRSRCPLK1 | |
| SCHEMBL27444270 | 0.77 | PLK1 (0.78) | CAMK2DABL1BCRSRCPLK1 | |
| SCHEMBL12801304 | 0.77 | ABL1 (0.58) | CAMK2DABL1BCRSRCPLK1 | |
| SCHEMBL3012944 | 0.76 | ABL1 (0.70) | CAMK2DABL1BCRSRCPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133214-B2 | Heteroalkyl linked pyrimidine derivatives | S*BIO PTE LTD (SG) | 2015-09-15 | — | — | US | disclosed |
| US-20120142680-A1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | S*BIO PTE LTD. (SG) | 2012-06-07 | — | — | US | disclosed |
| EP-1951730-B1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | S BIO PTE LTD (SG) | 2010-05-26 | — | — | EP | disclosed |
| US-20090258886-A1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | S*BIO PTE LTD. (SG) | 2009-10-15 | — | — | US | disclosed |
| EP-1951730-A1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | S*Bio Pte Ltd (SG) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007058628-A1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258886-A1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | TK1, TK2, DPYD | CAMK2D 1819/4885ABL1 252/4885BCR 798/4885 |
| US-20120142680-A1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | TK1, TK2, DPYD | CAMK2D 1819/4885ABL1 252/4885BCR 798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.