Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 6/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FSHR | P23945 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22803712 | 0.94 | RORC (0.43) | SYKRORCMAPKAPK2DGAT1TSHR | |
| SCHEMBL24215689 | 0.83 | RORC (0.41) | SYKRORCMAPKAPK2DGAT1TSHR | |
| SCHEMBL14923672 | 0.82 | RORC (0.47) | SYKRORCMAPKAPK2DGAT1MAP4K4 | |
| SCHEMBL23622903 | 0.82 | RORC (0.40) | SYKRORCMAPKAPK2DGAT1TSHR | |
| SCHEMBL29988952 | 0.82 | RORC (0.40) | SYKRORCMAPKAPK2DGAT1TSHR | |
| SCHEMBL29714434 | 0.77 | MGLL (0.30) | — | |
| SCHEMBL22778074 | 0.77 | MGLL (0.30) | — | |
| SCHEMBL22777989 | 0.76 | NPC1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL29046110 | 0.76 | — | — | |
| SCHEMBL23611992 | 0.74 | NAMPT (0.43) | RORCMAPKAPK2DGAT1MAP4K4IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182028-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM Due, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |