Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 1.00 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.72 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3540682 | 1.00 | KCNN3 (1.00) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3194298 | 1.00 | KCNN3 (1.00) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3540679 | 1.00 | KCNN3 (1.00) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL29354970 | 1.00 | KCNN3 (1.00) | KCNN3HDAC6KCNN1KCNN2 | |
| Hydrochloric Acid SCHEMBL29386908 | 0.99 | KCNN3 (0.97) | KCNN3HDAC6KCNN1KCNN2 | |
| Hydrochloric Acid SCHEMBL21713186 | 0.99 | KCNN3 (0.97) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3536825 | 0.96 | KCNN3 (0.93) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3542838 | 0.92 | KCNN3 (0.85) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3540207 | 0.86 | KCNN3 (0.74) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3545077 | 0.86 | KCNN3 (0.74) | KCNN3HDAC6KCNN1KCNN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119278197-A | Imidazole derivatives as potassium channel inhibitors | 阿塞西翁制药公司 | 2025-01-07 | — | — | CN | disclosed |
| WO-2024102883-A1 | METHODS OF TREATING, AMELIORATING, AND/OR PREVENTING STRESS-RELATED DISORDER | YALE UNIVERSITY (US) | 2024-05-16 | — | — | WO | disclosed |
| WO-2024033400-A1 | SK2 INHIBITOR FOR THE TREATMENT OF PANCREATIC CANCER | Institut National de la Santé et de la Recherche Médicale (FR) | 2024-02-15 | — | — | WO | disclosed |
| CN-117561247-A | Novel potassium channel inhibitors | 阿塞西翁制药公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111372928-B | Benzimidazole derivatives as potassium channel inhibitors | 阿塞西翁制药公司 | 2023-05-16 | — | — | CN | disclosed |