Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 1.00 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.72 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3540682 | 1.00 | KCNN3 (1.00) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3194298 | 1.00 | KCNN3 (1.00) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL30413342 | 1.00 | KCNN3 (1.00) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL29354970 | 1.00 | KCNN3 (1.00) | KCNN3HDAC6KCNN1KCNN2 | |
| Hydrochloric Acid SCHEMBL29386908 | 0.99 | KCNN3 (0.97) | KCNN3HDAC6KCNN1KCNN2 | |
| Hydrochloric Acid SCHEMBL21713186 | 0.99 | KCNN3 (0.97) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3536825 | 0.96 | KCNN3 (0.93) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3542838 | 0.92 | KCNN3 (0.85) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3540207 | 0.86 | KCNN3 (0.74) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3545077 | 0.86 | KCNN3 (0.74) | KCNN3HDAC6KCNN1KCNN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737167-B2 | 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels | NEUROSEARCH A/S (DK) | 2010-06-15 | — | — | US | claimed |
| EP-1776348-B1 | 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | NEUROSEARCH AS (DK) | 2008-05-28 | — | — | EP | claimed |
| US-20070197618-A1 | Novel 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels | NEUROSEARCH A/S (DK) | 2007-08-23 | — | — | US | claimed |
| US-7737167-B2 | 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels | NEUROSEARCH A/S (DK) | 2010-06-15 | — | — | US | disclosed |
| EP-1776348-B1 | 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | NEUROSEARCH AS (DK) | 2008-05-28 | — | — | EP | disclosed |
| US-20070197618-A1 | Novel 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels | NEUROSEARCH A/S (DK) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197618-A1 | Novel 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels | KCNN2, KCNN1, KCNN3 | KCNN3 3/4885HDAC6 657/4885KCNN1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.