Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.74 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.58 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3540205 | 1.00 | KCNN3 (0.74) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3540209 | 0.91 | KCNN3 (0.74) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3542602 | 0.87 | KCNN3 (0.72) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3542605 | 0.87 | KCNN3 (0.72) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3545074 | 0.86 | KCNN3 (0.74) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3194298 | 0.86 | KCNN3 (1.00) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL29354970 | 0.86 | KCNN3 (1.00) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL30413342 | 0.86 | KCNN3 (1.00) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3540682 | 0.86 | KCNN3 (1.00) | KCNN3HDAC6KCNN1KCNN2 | |
| SCHEMBL3540679 | 0.86 | KCNN3 (1.00) | KCNN3HDAC6KCNN1KCNN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737167-B2 | 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels | NEUROSEARCH A/S (DK) | 2010-06-15 | — | — | US | claimed |
| EP-1776348-B1 | 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | NEUROSEARCH AS (DK) | 2008-05-28 | — | — | EP | claimed |