Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.57 |
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.56 |
| ▸ | NMUR1 | Q9HB89 | 5/20 | 0.56 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.54 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.50 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.50 |
| ▸ | CALCR | P30988 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | MC5R | P33032 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
| ▸ | MC1R | Q01726 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29865201 | 0.89 | OPRM1 (0.56) | OPRD1OPRM1NMUR2NMUR1C5AR1 | |
| SCHEMBL29865057 | 0.89 | OPRM1 (0.56) | OPRD1OPRM1NMUR2NMUR1C5AR1 | |
| SCHEMBL30405782 | 0.89 | NMUR2 (0.57) | OPRD1OPRM1NMUR2NMUR1EPHA2 | |
| SCHEMBL29934595 | 0.88 | NMUR2 (0.58) | OPRD1NMUR2NMUR1NTSR1RAMP3 | |
| SCHEMBL30302482 | 0.86 | NMUR2 (0.62) | OPRD1OPRM1NMUR2NMUR1EPHA2 | |
| SCHEMBL30605471 | 0.86 | NMUR2 (0.63) | OPRM1NMUR2NMUR1NTSR1 | |
| SCHEMBL21571000 | 0.86 | NMUR2 (0.52) | OPRD1OPRM1NMUR2NMUR1C5AR1 | |
| SCHEMBL31325181 | 0.86 | OPRD1 (0.71) | OPRD1OPRM1NMUR2NMUR1C5AR1 | |
| SCHEMBL21579357 | 0.85 | NMUR2 (0.52) | OPRD1OPRM1NMUR2NMUR1C5AR1 | |
| SCHEMBL6889257 | 0.85 | OPRD1 (0.54) | OPRD1OPRM1NMUR2NMUR1C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655470-B2 | Diagnosing COL6-related disorders and methods for treating same | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-05-23 | — | — | US | disclosed |