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Sugi Predict / Compounds / SCHEMBL21571000

SCHEMBL21571000

SCHEMBL21571000

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NMUR2 Q9GZQ4 5/20 0.52
▸ NMUR1 Q9HB89 5/20 0.52
▸ IL23R Q5VWK5 1/20 0.49
▸ OPRD1 P41143 6/20 0.49
▸ OPRM1 P35372 4/20 0.49
▸ C5AR1 P21730 1/20 0.49
▸ RAMP3 O60896 1/20 0.48
▸ CALCR P30988 1/20 0.48
▸ TFPI P10646 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21579357 0.99 NMUR2 (0.52) NMUR2NMUR1IL23ROPRD1OPRM1
SCHEMBL21579361 0.87 NMUR2 (0.46) NMUR2NMUR1IL23ROPRD1OPRM1
SCHEMBL21570970 0.87 NTMT1 (0.51) OPRD1OPRM1
SCHEMBL21570973 0.87 NTMT1 (0.51) OPRD1OPRM1
SCHEMBL21570976 0.87 NTMT1 (0.51) OPRD1OPRM1
SCHEMBL21571015 0.87 NTMT1 (0.51) OPRD1OPRM1
SCHEMBL21579316 0.87 NTMT1 (0.51) OPRD1OPRM1
SCHEMBL30414371 0.86 OPRD1 (0.57) NMUR2NMUR1OPRD1OPRM1C5AR1
SCHEMBL29934595 0.86 NMUR2 (0.58) NMUR2NMUR1IL23ROPRD1RAMP3
SCHEMBL38657767 0.84 NMUR2 (0.47) NMUR2NMUR1OPRM1C5AR1RAMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085093-A1 INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF PURDUE RESEARCH FOUNDATION (US) 2026-03-26 — — US disclosed
US-20260078147-A1 INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF PURDUE RESEARCH FOUNDATION (US) 2026-03-19 — — US disclosed
US-12479887-B2 Inhibitors for protein n-terminal methyltransferase and uses thereof PURDUE RESEARCH FOUNDATION (US) 2025-11-25 — — US disclosed
US-20190352338-A1 INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF PURDUE RESEARCH FOUNDATION (US) 2019-11-21 — — US disclosed
US-20190352338-A1 INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF PURDUE RESEARCH FOUNDATION (US) 2019-11-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085093-A1 INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF GNMT, PRMT5, INMT NMUR2 3054/4885NMUR1 3092/4885IL23R 3722/4885
US-12479887-B2 Inhibitors for protein n-terminal methyltransferase and uses thereof GNMT, PRMT1, PRMT5 NMUR2 2597/4885NMUR1 2287/4885IL23R 4218/4885
US-20260078147-A1 INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF SMYD2, INMT, PRMT6 NMUR2 1201/4885NMUR1 989/4885IL23R 1776/4885
US-20190352338-A1 INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF GNMT, PRMT1, PRMT5 NMUR2 2597/4885NMUR1 2287/4885IL23R 4218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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