SCHEMBL30416820

SCHEMBL30416820

OCCN(CCO)c1nc(N2CCCCCCC2)c2nc(N(CCO)CCO)nc(N3CCCCCCC3)c2n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 19/20 1.00
ADORA3 P0DMS8 2/20 1.00
KDM4E B2RXH2 1/20 1.00
MEN1 O00255 1/20 1.00
PDE2A O00408 1/20 1.00
RGS12 O14924 1/20 1.00
SLC22A2 O15244 1/20 1.00
SLC22A1 O15245 1/20 1.00
ABCC4 O15439 1/20 1.00
ABCC5 O15440 1/20 1.00
PDE6D O43924 1/20 1.00
PDE8A O60658 1/20 1.00
GMNN O75496 1/20 1.00
USP2 O75604 1/20 1.00
PDE5A O76074 1/20 1.00
ABCB11 O95342 1/20 1.00
ALDH1A1 P00352 1/20 1.00
LMNA P02545 1/20 1.00
HSP90AA1 P07900 1/20 1.00
CHRM2 P08172 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridamole SCHEMBL3980595 1.00 SLC29A1 (1.00) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL16119 1.00 SLC29A1 (1.00) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL9743915 0.98 SLC29A1 (0.97) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL7362290 0.98 SLC29A1 (0.97) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL7998210 0.98 SLC29A1 (0.97) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL17044166 0.97 SLC29A1 (0.94) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL611283 0.95 SLC29A1 (0.91) SLC29A1ADORA3KDM4EMEN1PDE2A
SCHEMBL17017272 0.93 SLC29A1 (0.86) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL11234613 0.93 SLC29A1 (0.86) SLC29A1ADORA3KDM4EMEN1PDE2A
SCHEMBL6915061 0.93 SLC29A1 (0.86) SLC29A1ADORA3KDM4EMEN1PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233656-A2 METHODS OF ENHANCING ANTIBODY THERAPIES OHIO STATE INNOVATION FOUNDATION (US) 2024-11-14 WO disclosed
EP-4172149-A1 PROBENECID COMPOUNDS FOR THE TREATMENT OF INFLAMMASOME-MEDIATED LUNG DISEASE Bacainn Biotherapeutics, Ltd. (KY) 2023-05-03 EP disclosed