Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081101 | 0.82 | NR4A2 (0.54) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL7821339 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL30666368 | 0.82 | SMN1; SMN2 (0.49) | ALDH1A1HPGDHTTKMT2ATP53 | |
| SCHEMBL30666356 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL24710640 | 0.80 | RAB9A (0.42) | ALDH1A1HSD17B10HTTKMT2ATP53 | |
| SCHEMBL23384735 | 0.80 | NPC1 (0.42) | ALDH1A1HSD17B10HTTKMT2ATP53 | |
| SCHEMBL23360861 | 0.80 | GSK3B (0.56) | ALDH1A1HSD17B10HTTKMT2ATP53 | |
| SCHEMBL573257 | 0.79 | HCAR1 (0.53) | ALDH1A1HTTKDM4ENPC1RAB9A | |
| SCHEMBL30816535 | 0.79 | HCAR1 (0.53) | ALDH1A1HTTKDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28944721 | 0.79 | NPC1 (0.41) | ALDH1A1HSD17B10HTTKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203194-A | Novel compounds useful as STING agonists and uses thereof | 北京加科思新药研发有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-111971277-B | Benzothiophenes and related compounds as STING agonists | 默沙东有限责任公司 | 2023-06-06 | — | — | CN | disclosed |