Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25237122 | 1.00 | HDAC1 (0.44) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL9797400 | 0.83 | ALDH1A1 (0.48) | CA1CA2CA9ALDH1A1HPGD | |
| SCHEMBL7658479 | 0.83 | BRD4 (0.41) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL13732107 | 0.82 | ALDH1A1 (0.48) | CA1CA2CA9ALDH1A1HPGD | |
| SCHEMBL30684095 | 0.82 | USP2 (0.45) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL20754660 | 0.82 | USP2 (0.45) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL11561836 | 0.81 | POLB (0.49) | HDAC1CA1CA2CA9ALDH1A1 | |
| SCHEMBL13731847 | 0.79 | NISCH (0.47) | CA1CA2CA9ALDH1A1HPGD | |
| SCHEMBL30567319 | 0.79 | RXFP1 (0.51) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL25906721 | 0.79 | CA1 (0.43) | CA1CA2CA9ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250109126-A1 | DIHYDRO-OXAZOL DERIVATIVE COMPOUNDS | AC IMMUNE SA (CH) | 2025-04-03 | — | — | US | disclosed |
| EP-4452972-A1 | DIHYDRO-OXAZOL DERIVATIVE COMPOUNDS | AC Immune SA (CH) | 2024-10-30 | — | — | EP | disclosed |
| CN-118541366-A | Dihydrooxazole derivative compound | AC免疫有限公司 | 2024-08-23 | — | — | CN | disclosed |
| WO-2023118521-A1 | DIHYDRO-OXAZOL DERIVATIVE COMPOUNDS | AC IMMUNE SA (CH) | 2023-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250109126-A1 | DIHYDRO-OXAZOL DERIVATIVE COMPOUNDS | NLRP3, NLRP1, NOD1 | HDAC1 345/4885HDAC6 889/4885CA1 4146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.