Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | WNT3A | P56704 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30417052 | 0.93 | MEN1 (0.63) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL27486980 | 0.93 | MEN1 (0.63) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| Hydrochloric Acid SCHEMBL30416887 | 0.92 | MEN1 (0.61) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL30589562 | 0.82 | GAA (0.54) | MEN1KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL11838491 | 0.82 | MEN1 (0.56) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL27489099 | 0.79 | MEN1 (0.52) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL20610064 | 0.78 | SORT1 (0.67) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL1818730 | 0.78 | SORT1 (0.67) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL30417260 | 0.78 | SORT1 (0.67) | MEN1KMT2AKDM4EL3MBTL1CHRNB2 | |
| SCHEMBL5234574 | 0.76 | HCAR3 (0.63) | MEN1KMT2AKDM4EL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869350-B | Alkynyl compounds, their preparation and their therapeutic use | 赛诺菲 | 2023-05-02 | — | — | CN | claimed |
| CN-110869350-B | Alkynyl compounds, their preparation and their therapeutic use | 赛诺菲 | 2023-05-02 | — | — | CN | disclosed |