SCHEMBL30417366

SCHEMBL30417366

O=c1oc2ccccc2cc1-c1cc2ccccc2o1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.68
MAOB P27338 5/20 0.68
ALDH1A1 P00352 4/20 0.68
KDM4E B2RXH2 4/20 0.68
SMN1; SMN2 Q16637 5/20 0.60
NPC1 O15118 5/20 0.60
HPGD P15428 4/20 0.60
GAA P10253 2/20 0.60
GAPDH P04406 2/20 0.60
NCOA1 Q15788 1/20 0.60
NCOA3 Q9Y6Q9 1/20 0.60
ESR1 P03372 1/20 0.60
ESR2 Q92731 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
MAPT P10636 3/20 0.58
GLA P06280 2/20 0.58
TP53 P04637 2/20 0.58
CASP1 P29466 2/20 0.58
CASP7 P55210 2/20 0.58
HSD17B10 Q99714 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29517170 0.88 RAB9A (0.78) RAB9AMAOBALDH1A1KDM4ESMN1; SMN2
SCHEMBL24239998 0.87 MAOB (0.54) RAB9AMAOBALDH1A1KDM4ESMN1; SMN2
SCHEMBL30350030 0.87 MAOB (0.54) RAB9AMAOBALDH1A1KDM4ESMN1; SMN2
SCHEMBL12814246 0.83 LMNA (0.53) RAB9AMAOBALDH1A1KDM4ESMN1; SMN2
SCHEMBL14250607 0.82 RAB9A (0.60) RAB9AMAOBALDH1A1KDM4ESMN1; SMN2
SCHEMBL19497662 0.82 MAOB (0.63) RAB9AMAOBALDH1A1KDM4ENPC1
SCHEMBL177366 0.81 RAB9A (1.00) RAB9AMAOBALDH1A1KDM4ESMN1; SMN2
SCHEMBL30356319 0.81 RAB9A (1.00) RAB9AMAOBALDH1A1KDM4ESMN1; SMN2
SCHEMBL20358692 0.81 CYP19A1 (0.73) RAB9AMAOBALDH1A1KDM4ESMN1; SMN2
SCHEMBL12813997 0.80 LMNA (0.50) RAB9AMAOBALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4188921-A1 SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS Illumina Cambridge Limited (GB) 2023-06-07 EP disclosed