Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3041862 | 1.00 | EP300 (0.47) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL3409204 | 0.86 | CES2 (0.43) | PTPN1PPARGPPARDPPARAHSD17B10 | |
| SCHEMBL5157803 | 0.83 | EP300 (0.45) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL5157798 | 0.83 | EP300 (0.45) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL9540427 | 0.80 | EP300 (0.42) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL9540432 | 0.80 | EP300 (0.42) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL9652557 | 0.79 | FAAH (0.47) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL761753 | 0.78 | EP300 (0.39) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL11048910 | 0.78 | EP300 (0.39) | EP300TERTPTPN1PPARGPPARD | |
| SCHEMBL11048912 | 0.78 | EP300 (0.39) | EP300TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100172967-A1 | COMPOUND MODIFIED WITH GLYCEROL DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-07-08 | — | — | US | disclosed |
| US-7696359-B2 | Compound modified with glycerol derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-04-13 | — | — | US | disclosed |
| US-20060280784-A1 | Compound modified with glycerol derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-12-14 | — | — | US | disclosed |
| EP-1666486-A1 | COMPOUND MODIFIED WITH GLYCEROL DERIVATIVE | Kyowa Hakko Kogyo Co., Ltd (JP) | 2006-06-07 | — | — | EP | disclosed |
| EP-0285178-B1 | Mannobiose derivatives | MEITO SANGYO KK (JP) | 1997-02-12 | — | — | EP | disclosed |
| EP-0348942-B1 | LIPID MEMBRANE STRUCTURES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |
| US-5141751-A | Drug delivery for antitumor agent; mass-reproduction | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| US-4983725-A | Liposomes with affinity for liver cells | MEITO SANGYO CO., LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0348942-A2 | Lipid membrane structures | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1990-01-03 | — | — | EP | disclosed |
| EP-0285178-A2 | Mannobiose derivatives | MEITO SANGYO CO., LTD. (JP) | 1988-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060280784-A1 | Compound modified with glycerol derivative | MRGPRX1, MRGPRX2, NPC1L1 | EP300 1026/4885TERT 3473/4885PTPN1 2399/4885 |
| US-20100172967-A1 | COMPOUND MODIFIED WITH GLYCEROL DERIVATIVE | NPC1L1, SGMS1, SCARB1 | EP300 929/4885TERT 3513/4885PTPN1 2496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.