Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RHOA | P61586 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL325138 | 0.89 | NTRK1 (0.44) | LMNANTRK1ALDH1A1GAAHPGD | |
| SCHEMBL18487077 | 0.88 | LMNA (0.46) | LMNAALDH1A1GAAHPGDKMT2A | |
| SCHEMBL2211916 | 0.86 | MEN1 (0.42) | LMNAALDH1A1GAAKMT2AMAPT | |
| SCHEMBL3415407 | 0.82 | HSD11B1 (0.45) | NTRK1ALDH1A1HSD11B1KMT2APPARA | |
| SCHEMBL18487074 | 0.80 | GRM5 (0.43) | LMNANTRK1ALDH1A1HPGDKMT2A | |
| SCHEMBL3379780 | 0.80 | ACKR3 (0.38) | SCN9AKMT2A | |
| SCHEMBL303432 | 0.79 | LMNA (0.42) | LMNAALDH1A1GAAKMT2AMAPT | |
| SCHEMBL303301 | 0.78 | MEN1 (0.41) | LMNAALDH1A1GAAKMT2AMAPT | |
| SCHEMBL3377043 | 0.78 | MEN1 (0.47) | ALDH1A1GAAHSD11B1KMT2AL3MBTL1 | |
| SCHEMBL302949 | 0.78 | MEN1 (0.49) | ALDH1A1GAAHSD11B1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500836-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2342177-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-07-13 | — | — | EP | claimed |