SCHEMBL304192

SCHEMBL304192

C=Cn1c2ccc(Br)cc2c2cc(Br)ccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
KRAS P01116 3/20 0.37
DNM1 Q05193 4/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
P2RX3 P56373 1/20 0.34
ALDH1A1 P00352 3/20 0.33
KMT2A Q03164 2/20 0.33
BAX Q07812 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
MTOR P42345 1/20 0.33
HTT P42858 1/20 0.33
NCOA1 Q15788 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29716680 1.00 MAPT (0.42) MAPTKRASDNM1SMN1; SMN2P2RX3
SCHEMBL11066802 0.92 MAPT (0.38) MAPTKRASDNM1SMN1; SMN2P2RX3
SCHEMBL10953856 0.91 TSPO (0.43) MAPTKRASDNM1ALDH1A1KMT2A
SCHEMBL11649538 0.89 DNM1 (0.37) MAPTKRASDNM1SMN1; SMN2KMT2A
SCHEMBL11647864 0.89 MAPT (0.36) MAPTKRASDNM1SMN1; SMN2P2RX3
SCHEMBL11879601 0.89 DNM1 (0.37) MAPTKRASDNM1SMN1; SMN2ALDH1A1
SCHEMBL11882023 0.86 MEN1 (0.45) MAPTALDH1A1KMT2AHSD17B10KDM4E
SCHEMBL11882055 0.82 MAPT (0.46) MAPTKRASSMN1; SMN2KMT2ALMNA
SCHEMBL10954931 0.79 CHUK (0.41) MAPTKRASALDH1A1KMT2ACASP1
SCHEMBL28854324 0.75 MAPT (0.46) MAPTDNM1SMN1; SMN2P2RX3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110698347-B Preparation method of pentakis (dimethylamino) tantalum 浙江博瑞电子科技有限公司 2022-06-10 CN claimed
CN-112048165-A Environment-friendly waterproof material and preparation method thereof 郭琳 2020-12-08 CN claimed
CN-110698347-A Preparation method of pentakis (dimethylamino) tantalum 浙江博瑞电子科技有限公司 2020-01-17 CN claimed
EP-0324480-B1 Photopolymerizable compositions and elements for refractive index imaging DU PONT (US) 1994-04-13 EP claimed
EP-0324481-B1 STORAGE STABLE PHOTOPOLYMERIZABLE COMPOSITION FOR REFRACTIVE INDEX IMAGING E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-05 EP claimed
EP-0324482-B1 PROCESS OF FORMING REFLECTION HOLOGRAMS IN PHOTOPOLYMERIZABLE LAYERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-31 EP claimed
US-5098803-A Photopolymerization of a composition for holographic multilayer element E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-24 US claimed
US-4994347-A Polymeric binder, n-vinyl carbazole and photoinitiator system E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-02-19 US claimed
EP-0407773-A2 Improved holographic notch filters E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-16 EP claimed
EP-0404098-A2 Holographic optical elements having a reflection hologram formed in a photopolymer E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-12-27 EP claimed
US-4965152-A PHOTOPOLYMER FILMS IMAGED TO CONTAIN REFLECTION MIRROR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-23 US claimed
US-4950567-A Holographic optical combiners for head-up displays E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-21 US claimed
US-4942112-A HOLOGRAPHY, BINDERS, MONOMERS AND PHOTOINITIATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-07-17 US claimed
US-4942102-A MULTILAYER OPTICAL ELEMENT, BINDER OF POLYVINYL ACETAL, AN UNSATURATED MONOMER AND A PHOTOINITIATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-07-17 US claimed
EP-0324481-A2 Storage stable photopolymerizable composition for refractive index imaging E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-19 EP claimed
EP-0324482-A2 Process of forming reflection holograms in photopolymerizable layers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-19 EP claimed
EP-0324480-A2 Photopolymerizable compositions and elements for refractive index imaging E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-19 EP claimed
EP-0130088-A2 Plasma developable negative resist compositions for electron beam, X-ray and optical lithography TEXAS INSTRUMENTS INCORPORATED (US) 1985-01-02 EP claimed
US-4097277-A Photosensitive member having layer of vinyl carbazole polymer containing antimony chalcogen compound of antimony and sulfur CANON KABUSHIKI KAISHA (JA) 1978-06-27 US claimed
US-3989860-A Repair technique for photoreceptors XEROX CORPORATION (US) 1976-11-02 US claimed