Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4987809 | 0.89 | MAPT (0.40) | MAPTMAPK1SMN1; SMN2LMNAHTT | |
| SCHEMBL29716680 | 0.89 | MAPT (0.42) | DNM1MAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL304192 | 0.89 | MAPT (0.42) | DNM1MAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL11066802 | 0.82 | MAPT (0.38) | DNM1MAPTALDH1A1SMN1; SMN2KRAS | |
| SCHEMBL10953856 | 0.81 | TSPO (0.43) | DNM1MAPTALDH1A1MAPK1KRAS | |
| SCHEMBL4985558 | 0.81 | MAPT (0.41) | MAPTALDH1A1MAPK1LMNAHTT | |
| SCHEMBL11882023 | 0.80 | MEN1 (0.45) | MAPTALDH1A1ELANEHTTHTR6 | |
| SCHEMBL11647864 | 0.79 | MAPT (0.36) | DNM1MAPTSMN1; SMN2KRAS | |
| SCHEMBL11649538 | 0.79 | DNM1 (0.37) | DNM1MAPTMAPK1SMN1; SMN2KRAS | |
| SCHEMBL5532447 | 0.78 | ACHE (0.47) | DNM1MAPTALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3982935-A | CYANINE DYE BASE | ITEK CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |