Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 8/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24103542 | 0.90 | MEN1 (0.49) | MEN1KMT2AL3MBTL1KDM4CP2RX3 | |
| SCHEMBL30420188 | 0.79 | MEN1 (0.48) | MEN1KMT2AL3MBTL1KDM4CP2RX3 | |
| SCHEMBL24103862 | 0.73 | MEN1 (0.55) | MEN1KMT2AL3MBTL1KDM4CP2RX3 | |
| SCHEMBL24103333 | 0.71 | L3MBTL1 (0.45) | MEN1KMT2AL3MBTL1KDM4CP2RX3 | |
| SCHEMBL30419647 | 0.71 | TGFBR1 (0.32) | — | |
| SCHEMBL24103840 | 0.69 | KMT2A (0.45) | MEN1KMT2AKDM4CP2RX3NPC1 | |
| SCHEMBL15914347 | 0.69 | KMT2A (0.53) | MEN1KMT2AL3MBTL1KDM4CICAM1 | |
| SCHEMBL20764819 | 0.69 | MEN1 (0.53) | MEN1KMT2AL3MBTL1KDM4CICAM1 | |
| SCHEMBL9788 | 0.69 | MEN1 (0.53) | MEN1KMT2AL3MBTL1KDM4CICAM1 | |
| SCHEMBL15243991 | 0.69 | MEN1 (0.41) | MEN1KMT2AL3MBTL1KDM4CP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209664-A | Small molecule modulators of IL-17 | 利奥制药有限公司 | 2023-06-02 | — | — | CN | disclosed |