Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 3/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.57 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13220995 | 1.00 | S1PR2 (0.57) | S1PR2S1PR1S1PR3LPAR2SMN1; SMN2 | |
| SCHEMBL3042232 | 1.00 | S1PR2 (0.57) | S1PR2S1PR1S1PR3LPAR2SMN1; SMN2 | |
| SCHEMBL25807952 | 0.82 | S1PR2 (0.62) | S1PR2S1PR1S1PR3LPAR2RAB9A | |
| SCHEMBL10362438 | 0.80 | NR5A1 (0.59) | SMN1; SMN2MEN1RAB9AKMT2ANR5A1 | |
| SCHEMBL1437973 | 0.80 | RAB9A (0.51) | S1PR2S1PR1S1PR3LPAR2SMN1; SMN2 | |
| SCHEMBL26497466 | 0.80 | S1PR2 (0.57) | S1PR2S1PR1S1PR3LPAR2SMN1; SMN2 | |
| SCHEMBL17190624 | 0.79 | NR5A1 (0.53) | S1PR2S1PR1S1PR3LPAR2RAB9A | |
| SCHEMBL3712989 | 0.79 | ALDH1A1 (0.48) | S1PR2S1PR1S1PR3SMN1; SMN2MEN1 | |
| SCHEMBL9733079 | 0.78 | HRH3 (0.59) | S1PR1S1PR3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL725878 | 0.78 | ALDH1A1 (0.72) | S1PR2S1PR1S1PR3KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | ABBOTT LABORATORIES (US) | 2010-08-26 | — | — | US | claimed |
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | ABBOTT LABORATORIES (US) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | S1PR5, LPAR5, S1PR1 | S1PR2 6/4885S1PR1 3/4885S1PR3 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.