Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | FLT1 | P17948 | 2/20 | 0.50 |
| ▸ | FLT4 | P35916 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25213093 | 1.00 | PTGS1 (0.55) | PTGS1PTGS2MEN1KMT2AFLT1 | |
| SCHEMBL30423689 | 0.82 | PTGS1 (0.69) | PTGS1PTGS2MEN1KMT2ALMNA | |
| SCHEMBL25213185 | 0.82 | PTGS1 (0.69) | PTGS1PTGS2MEN1KMT2ALMNA | |
| SCHEMBL11806114 | 0.77 | PTGS1 (0.74) | PTGS1PTGS2MEN1KMT2ALMNA | |
| SCHEMBL25214387 | 0.76 | LMNA (0.67) | PTGS1PTGS2MEN1KMT2ALMNA | |
| SCHEMBL25210744 | 0.76 | PTGS1 (0.69) | PTGS1PTGS2MEN1KMT2ALMNA | |
| SCHEMBL30423638 | 0.76 | PTGS1 (0.69) | PTGS1PTGS2MEN1KMT2ALMNA | |
| SCHEMBL20359926 | 0.73 | FLT1 (0.61) | MEN1KMT2AFLT1FLT4KDR | |
| SCHEMBL30423184 | 0.73 | ALDH1A1 (0.43) | MEN1KMT2AFLT1FLT4KDR | |
| SCHEMBL25247871 | 0.73 | ALDH1A1 (0.43) | MEN1KMT2AFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |