Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25213185 | 1.00 | PTGS1 (0.69) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL30422735 | 0.82 | PTGS1 (0.55) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL25213093 | 0.82 | PTGS1 (0.55) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL577155 | 0.81 | PTGS1 (1.00) | PTGS1PTGS2MEN1KMT2ALMNA | |
| SCHEMBL25210744 | 0.80 | PTGS1 (0.69) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL25246486 | 0.80 | PTGS1 (0.69) | PTGS1PTGS2MEN1KMT2ALMNA | |
| SCHEMBL30423638 | 0.80 | PTGS1 (0.69) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL25213584 | 0.80 | PTGS1 (0.69) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL30423672 | 0.80 | PTGS1 (0.69) | PTGS1PTGS2MEN1KMT2APOLB | |
| SCHEMBL25219866 | 0.78 | LMNA (0.69) | PTGS1PTGS2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |