Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10560302 | 0.85 | PTPN1 (0.43) | PTPN1CYP19A1KDM4EALDH1A1PARK7 | |
| SCHEMBL9150766 | 0.79 | BACE1 (0.49) | BACE1PTPN1PTPRCPTPRFCDC25B | |
| SCHEMBL1408501 | 0.77 | BACE1 (0.64) | BACE1PTPN1PTPRCPTPRFCDC25B | |
| SCHEMBL20016082 | 0.74 | PTPN1 (0.41) | PTPN1CYP19A1KDM4EPARK7 | |
| SCHEMBL28277167 | 0.72 | BACE1 (0.57) | BACE1PTPN1PTPRCPTPRFCDC25B | |
| SCHEMBL29809142 | 0.72 | BACE1 (0.57) | BACE1PTPN1PTPRCPTPRFCDC25B | |
| SCHEMBL28506923 | 0.71 | MAP2K4 (0.34) | PTPN1LMNAHPGDMAOBKDM4E | |
| SCHEMBL31288113 | 0.71 | ALDH1A1 (0.39) | PTPN1CDC25BLMNAHPGDMAOB | |
| SCHEMBL27741769 | 0.71 | ALDH1A1 (0.39) | PTPN1CDC25BLMNAHPGDMAOB | |
| SCHEMBL10336242 | 0.69 | MAOA (0.44) | BACE1PTPN1PTPRCPTPRFCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143602-B | Indenone and indazolone derivatives with antioxidant activity, and synthetic method and application thereof | 西南大学 | 2024-10-22 | — | — | CN | disclosed |
| CN-116554104-A | Indenone and indazolone derivatives with antioxidant activity, and synthetic method and application thereof | 西南大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-116143602-A | Indenone and indazolone derivatives with antioxidant activity, and synthetic method and application thereof | 西南大学 | 2023-05-23 | — | — | CN | disclosed |