Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019970 | 0.79 | GRIA1 (0.45) | PTGS1PTGS2GRIA1GRIA2GRIA3 | |
| SCHEMBL4719825 | 0.79 | IDO1 (0.43) | PTGS1PTGS2GRIA1GRIA2GRIA3 | |
| SCHEMBL5128135 | 0.79 | MGLL (0.43) | GRIA1GRIA2GRIA3GRIA4MGLL | |
| SCHEMBL17802298 | 0.78 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4MEN1 | |
| SCHEMBL30516396 | 0.76 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL8506106 | 0.73 | DRD2 (0.41) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL1680730 | 0.73 | COMT (0.48) | PTGS2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL4670630 | 0.72 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4MGLL | |
| SCHEMBL27487817 | 0.72 | PTGS1 (0.50) | PTGS1PTGS2MGLLTUBB4ATUBB | |
| SCHEMBL6052596 | 0.70 | MGLL (0.39) | PTGS1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143677-B | Preparation method of key intermediate of voronoi fumarate | 北京济美堂医药研究有限公司 | 2026-03-20 | — | — | CN | disclosed |
| CN-119930492-A | Method for synthesizing 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde | 杭州乐敦科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-118978468-A | Synthesis method of voronoi fumarate intermediate | 武汉软件工程职业学院(武汉开放大学) | 2024-11-19 | — | — | CN | disclosed |
| CN-118852117-A | Synthesis method of voronoi fumarate | 浙江国邦药业有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118852116-A | Synthesis method of voronoi fumarate | 浙江国邦药业有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118108705-A | Preparation method of voronoi fumarate | 浙江工业大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-117647607-B | HPLC detection method for simultaneously determining related substances in 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde | 山东百诺医药股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-116178239-B | Synthesis method of 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde | 山东铂源药业股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117368371-A | Method for simultaneously measuring three isomer impurities of 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde | 淄博高新技术产业开发区生物医药研究院 | 2024-01-09 | — | — | CN | disclosed |
| CN-116621813-A | Preparation and purification method of voronoi fumarate | 合肥信风科技开发有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116514698-A | Preparation method and application of voronoi intermediate | 佛山奕安赛医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116178239-A | Synthesis method of 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde | 山东铂源药业股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-116143677-A | Preparation method of key intermediate of voronoi fumarate | 北京济美堂医药研究有限公司 | 2023-05-23 | — | — | CN | disclosed |