Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273123 | 0.98 | BLM (0.50) | BLMLMNAPTPN1ALOX15MEN1 | |
| SCHEMBL28746473 | 0.92 | LMNA (0.46) | BLMLMNAPTPN1ALOX15MEN1 | |
| SCHEMBL14321335 | 0.86 | BLM (0.52) | BLMLMNAPTPN1ALOX15MEN1 | |
| SCHEMBL15301878 | 0.84 | BLM (0.50) | BLMLMNAPTPN1ALOX15MEN1 | |
| SCHEMBL31211539 | 0.84 | BLM (0.50) | BLMLMNAPTPN1ALOX15MEN1 | |
| SCHEMBL3780110 | 0.84 | BLM (0.50) | BLMLMNAPTPN1ALOX15MEN1 | |
| SCHEMBL2257584 | 0.83 | BLM (0.48) | BLMLMNAPTPN1ALOX15MEN1 | |
| SCHEMBL6273124 | 0.83 | LMNA (0.49) | BLMLMNAMEN1KMT2AACE2 | |
| SCHEMBL2347747 | 0.82 | BLM (0.48) | BLMLMNAPTPN1ALOX15MEN1 | |
| SCHEMBL4714338 | 0.82 | BLM (0.48) | BLMLMNAPTPN1ALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |