Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273123 | 0.94 | BLM (0.50) | LMNABLMPTPN1CA1MEN1 | |
| SCHEMBL30423744 | 0.92 | BLM (0.53) | LMNABLMACE2PTPN1CA1 | |
| SCHEMBL8515232 | 0.87 | LMNA (0.49) | LMNABLMACE2MEN1KMT2A | |
| SCHEMBL6273124 | 0.83 | LMNA (0.49) | LMNABLMACE2MEN1KMT2A | |
| SCHEMBL1739617 | 0.81 | ACE2 (0.42) | LMNAACE2CA1CYP3A4ALDH1A1 | |
| SCHEMBL27552374 | 0.80 | KDM4C (0.34) | LMNABLMKDM4CKDM4APHF8 | |
| SCHEMBL22577750 | 0.80 | ALDH1A1 (0.42) | LMNABLMPTPN1CA1CYP3A4 | |
| SCHEMBL15028271 | 0.80 | LMNA (0.48) | LMNABLMACE2PTPN1FAAH | |
| SCHEMBL2257584 | 0.79 | BLM (0.48) | LMNABLMPTPN1KDM4CMEN1 | |
| SCHEMBL28605931 | 0.79 | TLR4 (0.36) | LMNABLMKDM4CKDM4APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1343650-A | Anticancer compound with particular structure | YANG ZHENHUA (CN) | 2002-04-10 | — | — | CN | disclosed |