Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17042584 | 1.00 | MAPK1 (0.48) | MAPK1PKMRAB9AKDM4EALDH1A1 | |
| SCHEMBL30371569 | 0.88 | MAPT (0.44) | MAPK1PKMRAB9AKDM4EALDH1A1 | |
| SCHEMBL20529670 | 0.88 | MAPT (0.44) | MAPK1PKMRAB9AKDM4EALDH1A1 | |
| SCHEMBL18477376 | 0.85 | MAPT (0.50) | MAPK1PKMRAB9AKDM4EALDH1A1 | |
| SCHEMBL6896249 | 0.82 | MAPT (0.62) | MAPK1PKMRAB9AKDM4EALDH1A1 | |
| SCHEMBL1889528 | 0.81 | PKM (0.45) | MAPK1PKMRAB9AKDM4EALDH1A1 | |
| SCHEMBL594213 | 0.80 | HCAR3 (0.61) | MAPK1PKMRAB9AKDM4EALDH1A1 | |
| SCHEMBL29473160 | 0.79 | RAB9A (0.48) | MAPK1PKMRAB9AKDM4EALDH1A1 | |
| SCHEMBL8799901 | 0.79 | RAB9A (0.48) | MAPK1PKMRAB9AKDM4EALDH1A1 | |
| SCHEMBL1957506 | 0.78 | MAPT (0.62) | PKMALDH1A1TDP1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4511375-A1 | BICYCLIC COMPOUNDS | Aligos Therapeutics, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| CN-119053599-A | Bicyclic compounds | 安力高医药股份有限公司 | 2024-11-29 | — | — | CN | disclosed |
| WO-2023205653-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| CN-116075510-A | 1H-benzo [ d ] imidazole derivatives as TLR9 inhibitors for the treatment of fibrosis | 百时美施贵宝公司 | 2023-05-05 | — | — | CN | disclosed |