Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL5 | Q9Y5K5 | 5/20 | 0.56 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.56 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25215900 | 1.00 | UCHL5 (0.56) | UCHL5UCHL1UCHL3HDAC6HDAC3 | |
| SCHEMBL25348959 | 0.90 | HDAC6 (0.58) | UCHL5UCHL1UCHL3HDAC6HDAC3 | |
| SCHEMBL25350756 | 0.87 | HDAC6 (0.53) | UCHL5HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL30409208 | 0.87 | HDAC6 (0.58) | UCHL5UCHL1UCHL3HDAC6HDAC3 | |
| SCHEMBL31535158 | 0.87 | ALOX5 (0.48) | UCHL5UCHL1UCHL3HDAC6HDAC3 | |
| SCHEMBL25351971 | 0.87 | ALOX5 (0.48) | UCHL5UCHL1UCHL3HDAC6HDAC3 | |
| SCHEMBL25352274 | 0.87 | HDAC6 (0.58) | UCHL5UCHL1UCHL3HDAC6HDAC3 | |
| SCHEMBL24215835 | 0.86 | HDAC6 (0.62) | HDAC6HDAC8MEN1KMT2ACASP3 | |
| SCHEMBL25216837 | 0.86 | HDAC6 (0.55) | HDAC6CYP19A1 | |
| SCHEMBL24216740 | 0.86 | HDAC6 (0.55) | HDAC6MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | claimed |
| CN-116157398-A | 2- (4- ((5- (benzo [ b ] thiophen-3-yl) -1H-tetrazol-1-yl) methyl) phenyl) -5- (difluoromethyl) -1,3, 4-oxadiazole derivatives and similar compounds as selective inhibitors of histone deacetylase 6 (HDAC 6) for the treatment of, for example, peripheral neuropathy | 意大发马克股份公司 | 2023-05-23 | — | — | CN | claimed |
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-116157398-A | 2- (4- ((5- (benzo [ b ] thiophen-3-yl) -1H-tetrazol-1-yl) methyl) phenyl) -5- (difluoromethyl) -1,3, 4-oxadiazole derivatives and similar compounds as selective inhibitors of histone deacetylase 6 (HDAC 6) for the treatment of, for example, peripheral neuropathy | 意大发马克股份公司 | 2023-05-23 | — | — | CN | disclosed |