Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.42 |
| ▸ | ADH1C | P00326 | 2/20 | 0.42 |
| ▸ | ADH1A | P07327 | 2/20 | 0.42 |
| ▸ | ADH4 | P08319 | 2/20 | 0.42 |
| ▸ | ADH7 | P40394 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3045141 | 0.98 | ADH1B (0.46) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL28087567 | 0.98 | ADH1B (0.46) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL27855045 | 0.98 | ADH1B (0.46) | ADH1BADH1CADH1AADH4ADH7 | |
| Hydrochloric Acid SCHEMBL28112865 | 0.98 | ADH1B (0.41) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL385559 | 0.94 | TSHR (0.40) | ADH1BADH1CADH1AADH4ADH7 | |
| Hydrochloric Acid SCHEMBL29133121 | 0.92 | TSHR (0.39) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL103021 | 0.85 | — | — | |
| SCHEMBL5441114 | 0.83 | LMNA (0.31) | TSHRSMN1; SMN2 | |
| SCHEMBL3024812 | 0.82 | ACE2 (0.44) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL8634231 | 0.81 | LMNA (0.41) | ADH1BADH1CADH1AADH4ADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689611-A | METHOD FOR PRODUCING ORGANIC COMPOUND | 株式会社钟化 | 2019-04-26 | — | — | CN | claimed |
| CN-114085167-A | Preparation method of impurity TS-3A | 华中药业股份有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-110446700-A | Compound | GLAXOSMITHKLINE IP DEV LTD | 2019-11-12 | — | — | CN | disclosed |
| CN-105705492-B | 5,6,7, 8-tetrahydro-5, 8-methanocinnoline derivatives as RORC modulators for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-106458859-B | Novel EP4 agonists as therapeutic compounds | 阿勒根公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-109689611-A | METHOD FOR PRODUCING ORGANIC COMPOUND | 株式会社钟化 | 2019-04-26 | — | — | CN | disclosed |
| CN-106458859-A | Novel EP 4 agonists as therapeutic compounds | 阿勒根公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106232598-A | Cycloalkyl-linked diheterocyclic derivatives | 辉瑞公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-104619709-B | Imidazopyridine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-11-09 | — | — | CN | disclosed |
| EP-2045256-A1 | 2'-CYANOPYRIMIDINE NUCLEOSIDE COMPOUND | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 2009-04-08 | — | — | EP | disclosed |
| CN-1994301-A | Heterocyclic compounds which are active as inhibitors of beta lactamases | AVENTIS PHARMA SA (FR) | 2007-07-11 | — | — | CN | disclosed |
| CN-1655781-A | Novel heterocyclic compounds having beta-lactamase inhibitor activity | AVENTIS PHARMA SA (FR) | 2005-08-17 | — | — | CN | disclosed |
| EP-0799830-B1 | Imidazothiazol derivatives as components of liquid crystalline mixtures | ROLIC AG (CH) | 2002-05-29 | — | — | EP | disclosed |
| US-5851425-A | Imidazothiazoles | ROLIC AG (CH) | 1998-12-22 | — | — | US | disclosed |
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0799830-A1 | Imidazothiazol derivatives as components of liquid crystalline mixtures | Rolic AG (CH) | 1997-10-08 | — | — | EP | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |
| US-4859759-A | Siloxane containing benzotriazolyl/tetraalkylpiperidyl substituent | KIMBERLY-CLARK CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |