Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.46 |
| ▸ | ADH1C | P00326 | 2/20 | 0.46 |
| ▸ | ADH1A | P07327 | 2/20 | 0.46 |
| ▸ | ADH4 | P08319 | 2/20 | 0.46 |
| ▸ | ADH7 | P40394 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28087567 | 1.00 | ADH1B (0.46) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL27855045 | 1.00 | ADH1B (0.46) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL3042552 | 0.98 | ADH1B (0.42) | ADH1BADH1CADH1AADH4ADH7 | |
| Hydrochloric Acid SCHEMBL28112865 | 0.96 | ADH1B (0.41) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL385559 | 0.92 | TSHR (0.40) | ADH1BADH1CADH1AADH4ADH7 | |
| Hydrochloric Acid SCHEMBL29133121 | 0.90 | TSHR (0.39) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL103021 | 0.83 | — | — | |
| SCHEMBL27480469 | 0.82 | ACE2 (0.47) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL27721174 | 0.82 | ACE2 (0.47) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL3034938 | 0.82 | ACE2 (0.47) | ADH1BADH1CADH1AADH4ADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207515-B | Pyrazine compounds for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2019-05-28 | — | — | CN | claimed |
| CN-104926736-B | A kind of synthetic method of Fluoxastrobin and its intermediate | 重庆紫光化工股份有限公司 | 2019-05-17 | — | — | CN | claimed |
| CN-103917095-A | Combination treatments for hepatitis c | GLAXOSMITHKLINE LLC | 2014-07-09 | — | — | CN | claimed |
| CN-110357782-B | Preparation method of medium-long chain fatty alcohol and ester thereof | 中国科学技术大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-111689854-A | Process for preparing 3-carbonyl-bicyclo [2.2.2] octane-2-formate | 广东莱佛士制药技术有限公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-110446711-A | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD | 2019-11-12 | — | — | CN | disclosed |
| CN-110357782-A | A kind of preparation method of middle long-chain fatty alcohol and its ester | 中国科学技术大学 | 2019-10-22 | — | — | CN | disclosed |
| CN-106854205-B | Inhibitors of influenza virus replication and methods of use and uses thereof | 广东东阳光药业有限公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-109843894-A | Beta-lactamase inhibitor | 诺华股份有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-107207515-B | Pyrazine compounds for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-109748915-A | Inhibitors of influenza viruses replication and its application method and purposes | 广东东阳光药业有限公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-101406471-A | Novel heterocyclic compounds which are active as inhibitors of beta-lactamases | AVENTIS PHARMA SA (FR) | 2009-04-15 | — | — | CN | disclosed |
| CN-1994301-A | Heterocyclic compounds which are active as inhibitors of beta lactamases | AVENTIS PHARMA SA (FR) | 2007-07-11 | — | — | CN | disclosed |
| CN-1662242-A | Pharmaceutical compositions for the treatment of diseases related to neurotrophines | MIMETECH S R L (IT) | 2005-08-31 | — | — | CN | disclosed |
| CN-1655781-A | Novel heterocyclic compounds having beta-lactamase inhibitor activity | AVENTIS PHARMA SA (FR) | 2005-08-17 | — | — | CN | disclosed |
| US-6670307-B2 | Such as 2-(2,6-difluorophenyl)-4-(4-(2-ethoxypyridin-5-yl) phenyl)oxazoline; for administration to livestock | HOECHST SCHERING AGREVO GMBH (DE) | 2003-12-30 | — | — | US | disclosed |
| US-20030119806-A1 | Azetidine derivatives, processes for their preparation and their use as pesticides | BAYER CROPSCIENCE S.A. (FR) | 2003-06-26 | — | — | US | disclosed |
| US-20020068828-A1 | 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides | BAYER CROPSCIENCE AG (DE) | 2002-06-06 | — | — | US | disclosed |
| US-6300333-B1 | COMPOUNDS AS FUNGICIDES, MITICIDES OR INSECTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-10-09 | — | — | US | disclosed |
| US-6265350-B1 | CONTROLLING HARMFUL FUNGI, INSECTS, ACARINA, MOLLUSKS AND NEMATODES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119806-A1 | Azetidine derivatives, processes for their preparation and their use as pesticides | DDT, CHRM1, CNTN1 | ADH1B 2270/4885ADH1C 233/4885ADH1A 1366/4885 |
| US-20020068828-A1 | 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides | MT-CO1, OXA1L, MT-CO3 | ADH1B 2795/4885ADH1C 538/4885ADH1A 1191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.