SCHEMBL30426923

SCHEMBL30426923

CC(C)(C)OC(=O)/C(C#N)=C/c1cn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nccc(F)c12

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 4/20 0.36
▸ SNCA P37840 4/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ LMNA P02545 1/20 0.35
▸ PTGDR2 Q9Y5Y4 1/20 0.35
▸ RPS6KA3 P51812 2/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ THRB P10828 1/20 0.34
▸ SLC16A1 P53985 3/20 0.33
▸ ENPP2 Q13822 2/20 0.32
▸ JAK3 P52333 1/20 0.32
▸ ESRRA P11474 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30426708 0.92 APP (0.45) APPSNCAALDH1A1LMNAPTGDR2
SCHEMBL24165405 0.92 APP (0.45) APPSNCAALDH1A1LMNAPTGDR2
SCHEMBL22201852 0.90 MIF (0.41) APPSNCAALDH1A1LMNAKDM4E
SCHEMBL30426404 0.90 MIF (0.41) APPSNCAALDH1A1LMNAKDM4E
SCHEMBL22201850 0.88 APP (0.38) APPSNCAALDH1A1LMNAPTGDR2
SCHEMBL30426742 0.88 APP (0.38) APPSNCAALDH1A1LMNAPTGDR2
SCHEMBL30340916 0.86 APP (0.49) APPSNCAALDH1A1LMNAKDM4E
SCHEMBL29919467 0.86 APP (0.49) APPSNCAALDH1A1LMNAKDM4E
SCHEMBL22201821 0.82 MIF (0.41) APPSNCAALDH1A1LMNAKDM4E
SCHEMBL20615238 0.82 PTP4A1 (0.41) ALDH1A1LMNAKDM4ETHRBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240327400-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-10-03 — — US disclosed
EP-4172158-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH The Regents of the University of California (US) 2023-05-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240327400-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH PC, FH, PDK1 APP 2860/4885SNCA 4854/4885ALDH1A1 614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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