Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.60 |
| ▸ | GRM8 | O00222 | 2/20 | 0.60 |
| ▸ | GRM6 | O15303 | 2/20 | 0.60 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.60 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.60 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.60 |
| ▸ | GRM5 | P41594 | 1/20 | 0.60 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.60 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.60 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.60 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.60 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.60 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.60 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22164119 | 0.85 | ALOX15 (0.76) | GSRGRM8GRM6GRM7GRM4 | |
| SCHEMBL27872833 | 0.85 | ALOX15 (0.76) | GSRGRM8GRM6GRM7GRM4 | |
| SCHEMBL4361742 | 0.79 | GSR (0.62) | GSRGRM8GRM6GRM7GRM4 | |
| SCHEMBL3323804 | 0.79 | GSR (0.62) | GSRGRM8GRM6GRM7GRM4 | |
| SCHEMBL16994472 | 0.79 | GSR (0.62) | GSRGRM8GRM6GRM7GRM4 | |
| SCHEMBL14617601 | 0.79 | GSR (0.62) | GSRGRM8GRM6GRM7GRM4 | |
| SCHEMBL17602386 | 0.77 | GSR (0.60) | GSRGRM8GRM6GRM7GRM4 | |
| SCHEMBL22734891 | 0.77 | ALOX15 (0.64) | GSRGRM8GRM6GRM7GRM4 | |
| SCHEMBL15342759 | 0.77 | GRIK1 (0.60) | GSRGRM8GRM6GRM7GRM4 | |
| SCHEMBL10076866 | 0.77 | GRIK1 (0.60) | GSRGRM8GRM6GRM7GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012153125-A1 | NOVEL COMPOUNDS AND METHODS FOR USE IN MEDICINE | ASTON UNIVERSITY (GB) | 2012-11-15 | — | — | WO | disclosed |
| US-7723307-B2 | Amino acid derivatives and pharmaceutical uses thereof | ASTON UNIVERSITY (GB) | 2010-05-25 | — | — | US | disclosed |
| US-20080200511-A1 | Novel Compounds and Methods of Using the Same | ASTON UNIVERSITY (GB) | 2008-08-21 | — | — | US | disclosed |
| EP-1648924-B1 | DIPEPTIDE TRANSGLUTAMINASE INHIBITORS AND METHODS OF USING THE SAME | UNIV ASTON (GB) | 2008-07-30 | — | — | EP | disclosed |
| EP-1648924-A2 | DIPEPTIDE TRANSGLUTAMINASE INHIBITORS AND METHODS OF USING THE SAME | The Nottingham Trent University (GB) | 2006-04-26 | — | — | EP | disclosed |
| WO-2004113363-A2 | DIPEPTIDE TRANSGLUTAMINASE INHIBITORS AND METHODS OF USING THE SAME | THE NOTTINGHAM TRENT UNIVERSITY (GB) | 2004-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200511-A1 | Novel Compounds and Methods of Using the Same | F3, IL4I1, TPMT | GSR 216/4885GRM8 2640/4885GRM6 2319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.