Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.60 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.60 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.60 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.60 |
| ▸ | GSR | P00390 | 2/20 | 0.60 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.60 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.60 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.60 |
| ▸ | GRM8 | O00222 | 1/20 | 0.60 |
| ▸ | GRM6 | O15303 | 1/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.60 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | GRM5 | P41594 | 1/20 | 0.60 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.60 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.60 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15342759 | 1.00 | GRIK1 (0.60) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| SCHEMBL16577954 | 0.90 | GRIK1 (0.54) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| SCHEMBL22164119 | 0.85 | ALOX15 (0.76) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| SCHEMBL27872833 | 0.85 | ALOX15 (0.76) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| SCHEMBL3486168 | 0.85 | GSR (0.55) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| SCHEMBL7362969 | 0.84 | GSR (0.53) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| SCHEMBL7791775 | 0.84 | GSR (0.53) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| SCHEMBL12998158 | 0.82 | TDP1 (0.39) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| Glutamic Acid SCHEMBL564069 | 0.82 | GRM8 (0.82) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| SCHEMBL19455873 | 0.82 | ALOX15 (0.41) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807664-B2 | Method for producing cyclic organic compound | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-07 | — | — | US | disclosed |
| WO-2020159448-A1 | MOLECULAR RENAL PROBES FOR DETECTING ACUTE KIDNEY INJURY | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2020-08-06 | — | — | WO | disclosed |
| US-9593079-B2 | Stabilized multi-functional antioxidant compounds and methods of use | XPD HOLDINGS, LLC (US) | 2017-03-14 | — | — | US | disclosed |
| US-20170015990-A1 | HYBRID POLYKETIDE SYNTHASES | ENERGY, UNITED STATES DEPARTMENT OF | 2017-01-19 | — | — | US | disclosed |
| US-20160185718-A1 | Stabilized Multi-Functional Antioxidant Compounds and Methods of Use | XPD HOLDINGS, LLC | 2016-06-30 | — | — | US | disclosed |
| US-20160058728-A1 | CANCER STARVATION THERAPY | SERBIG PHARMACEUTICALS CORP. (PR) | 2016-03-03 | — | — | US | disclosed |
| WO-2012148550-A1 | PRODRUGS OF THERAPEUTIC COMPOUNDS | MYREXIS, INC. (US) | 2012-11-01 | — | — | WO | disclosed |
| EP-2468744-A2 | Inhibitors of serine proteases, particularly HCV NS3-NS4A protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160058728-A1 | CANCER STARVATION THERAPY | TUFM, TFAM, GFM1 | GRIK1 1613/4885SLC1A3 904/4885SLC1A2 1282/4885 |
| US-20160185718-A1 | Stabilized Multi-Functional Antioxidant Compounds and Methods of Use | SOD1, GPX4, SOD3 | GRIK1 2928/4885SLC1A3 4340/4885SLC1A2 4464/4885 |
| US-11807664-B2 | Method for producing cyclic organic compound | SCTR, CTRC, DCXR | GRIK1 4686/4885SLC1A3 4799/4885SLC1A2 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.